Overzicht gehonoreerde projecten Open Ronde 4

• EFFICACY OF OPTIMIZED THIOPURINE THERAPY IN ULCERATIVE COLITIS

• Tight control dose-reductions of biologics in psoriasis patients with low disease activity: a randomized pragmatic trial

• Introduction of a biomarker-guided treatment-and-stop-strategy for recombinant IL-1receptor antagonist (anakinra) in patients with systemic Juvenile Idiopathic Arthritis

• Low dose aspirin in the Prevention of Recurrent Spontaneous Preterm Labour – the APRIL study

• Zoledronate as disease modifier in osteoarthritis

• Augmentation with raloxifene: towards a better outcome for patients with schizophrenia spectrum disorders

• Efficacy of paracetamol, NSAIDs and advice for patients with acute low back pain: a placebo controlled trial (PACE-plus)

• Are ursodeoxycholic acid, mesalazine, thiopurines, and non-steroidals efficacious and cost-effective in primary sclerosing cholangitis? A nationwide study.

• Safety and pharmacokinetics of antipsychotics in children with autism

• The effect of tocolysis with nifedipine or atosiban on infant development (APOSTEL III follow-up)

• TailoRing anti-androgEn therapy For metastatic castration resistant prostate cancer based on early tumor response markers In combiNation with drug Exposure measurement (REFINE-project)

• Insulin regime versus oral therapy for diabetes in pregnancy: the SUGAR-DIP trial

• Analgosedation after cardiac surgery in infants: A "model-based" nation-wide randomized controlled trial.

• Increased cancer incidence in patients with type 2 diabetes using sulphonylureas?

• Right dose, right now: using big data for bedside personalised drug dosing

• Rationalizing pharmacotherapy via performance feedback and computerized decision support in a national network of Intensive Care Units

• Individualized dosing of AMInoglycosides and Glycopeptide antibiotics in (morbidly) Obese patients (AMIGO): clinical studies and implementation in clinical practice

• Repositioning bumetanide for the treatment of Autism Spectrum Disorder

• STRAP -Study to Reduce Antibiotic prescription in childhood Pneumonia: implementation of a validated decision rule to target antibiotic prescription in children with suspected community acquired pneumonia

Over het gebruik van geneesmiddelen door kinderen, ouderen, zwangeren, mensen met zeldzame aandoeningen en ter voorkoming van antimicrobiële resistentie is meer wetenschappelijke onderbouwde kennis nodig.

• STRAP -Study to Reduce Antibiotic prescription in childhood Pneumonia: implementation of a validated decision rule to target antibiotic prescription in children with suspected community acquired pneumonia

• Introduction of a biomarker-guided treatment-and-stop-strategy for recombinant IL-1receptor antagonist (anakinra) in patients with systemic Juvenile Idiopathic Arthritis

• Safety and pharmacokinetics of antipsychotics in children with autism

• The effect of tocolysis with nifedipine or atosiban on infant development (APOSTEL III follow-up)

• Repositioning bumetanide for the treatment of Autism Spectrum Disorder

• Analgosedation after cardiac surgery in infants: A "model-based" nation-wide randomized controlled trial.

• Low dose aspirin in the Prevention of Recurrent Spontaneous Preterm Labour – the APRIL study

• Insulin regime versus oral therapy for diabetes in pregnancy: the SUGAR-DIP trial

• TailoRing anti-androgEn therapy For metastatic castration resistant prostate cancer based on early tumor response markers In combiNation with drug Exposure measurement (REFINE-project)

• Introduction of a biomarker-guided treatment-and-stop-strategy for recombinant IL-1receptor antagonist (anakinra) in patients with systemic Juvenile Idiopathic Arthritis

• STRAP -Study to Reduce Antibiotic prescription in childhood Pneumonia: implementation of a validated decision rule to target antibiotic prescription in children with suspected community acquired pneumonia

• Individualized dosing of AMInoglycosides and Glycopeptide antibiotics in (morbidly) Obese patients (AMIGO): clinical studies and implementation in clinical practice

• Right dose, right now: using big data for bedside personalised drug dosing