Focus area 1. Predictive diagnostics and treatment
Theme 1: Treatment
- ReCOVer: A randomized controlled trial testing the efficacy of cognitive behavioural therapy for preventing chronic postinfectious fatigue among patients diagnosed with COVID-19 disease
Prof. J.A. (Hans) Knoop
Amsterdam University Medical Center - location AMC - BTK inhibition to prevent hyperinflammatory syndrome in COVID-19 patients
Dr O.B.J. (Odilia) Corneth
Erasmus Medical Center - COVID-19 and ischemic stroke - How to tame a dozing monster
Prof. F. E. (Frank-Erik) de Leeuw
Leiden University Medical Center
Theme 2. Diagnostics of infection
- SARSLIVA and utility of saliva in diagnosis for wide scale testing, including viral and SARS-CoV-2 antibody detection in pre- and asymptomatic persons and follow-up of infections in COVID-19 patient; a house hold study
Dr S.F. (Steven) van Lelyveld
Spaarne Gasthuis
Theme 3. Risk analysis and prognostics
- Prospective cohort study of non-hospitalised COVID-19 patients: determining length of isolation and patient clinical development at home (COVID-HOME study)
Dr A. (Adriana) Tami
University Medical Center Groningen - Obesity as an amplifier of inflammation and organ injury in SARS-CoV-2 infected patients: prognostic potential and therapeutic target Thema 3: Risicoanalyse en prognostiek
Dr J. (Jill) Moser
University Medical Center Groningen - Identification of COVID-19 patients with high Risk of mortality at ICU admiSsion – IRIS-study
Prof. N.F. (Nicolet) de Keizer
Nationale Intensive Care Evaluatie - Clinical prediction models for COVID-19: development, international validation and use
Dr ir. D. (David) van Klaveren
Erasmus Medical Center
Theme 4. Virus, immunity, immune response and pathogenesis
- Integrative analysis of multi-omics longitudinal data to identify effective strategies for the prediction and treatment of COVID-19
Dr V.K. (Vinod Kumar) Magadi Gopalaiah
Radboud University Medical Center - Understanding the two faces of the COVID-19 immune response to predict clinical course and define strategies for early and late phase intervention
Dr S. (Stefan) Nierkens and dr F (Femke) van Wijk
University Medical Center Utrecht - BCG vaccination to minimise COVID-19 disease severity and duration
T. (Thijs) ten Doesschate, MSc
University Medical Center - Therapeutic inhibition of excessive lung inflammation induced by anti-SARS-CoV-2 antibodies
Dr J. (Jeroen) den Dunnen
Amsterdam University Medical Center - location AMC - Immunity against SARS-CoV-2 in immune-suppressed patients: increased risk of insufficient immunological memory or sufficient protection against re-infection?
Prof. T.W. (Taco) Kuijpers
Amsterdam University Medical Center - location AMC - Establishment and duration of protective immunity against SARS-CoV-2, in relation to severity of SARS-CoV-2 infection
Prof. C.E. (Ellen) van der Schoot
Sanquin Research - WikiPathways as a platform for COVID-19 pathway models. Identification of underlying mechanisms explaining differences in host immune response, disease severity and detection of mechanisms for targeted (drug) treatment
Dr M. (Martina) Kutmon
Maastricht University Medical Center+ - Identifying pathogenesis of COVID-19 pathology in the Dutch population and unravelling differences in pathogenetic mechanisms in high- and low-risk groups
Dr J. (Jan) von der Thüsen
Erasmus Medical Center - A virus-free high-throughput platform for studying coronavirus replication inhibitors
Dr D. (Dirk) Eggink
Amsterdam University Medical Center - location AMC - Altered IgG fucosylation driving pathologies in COVID-19: Relevance for diagnosis and therapeutics
Dr G. (Gestur) Vidarsson
Sanquin (Blood Supply) - Measuring, understanding & reducing respiratory droplet spreading
Prof. D. (Detlef) Lohse
University of Twente
Theme: Studies into clinical treatments
- The COUNTER-COVID study: Oral imatinib to reverse pulmonary vascular leak and disease burden in COVID-19
Dr HJ. (Harm-Jan) Bogaard
Amsterdam University Medical Center - location VUmc - A phase-2-study, pivotal for clinical development of lanadelumab for treatment of COVID-19
Dr R.J.M. (Roger) Brüggemann and dr F. (Frank) van de Veerdonk
Radboud University Medical Center - The PRAETORIAN-COVID study: A double-blind, placebo-controlled randomized clinical trial with valsartan for PRevention of Acute rEspiraTORy dIstress syndrome in hospitAlized patieNts with SARS-COV-2 Infection Disease
Dr D.H.F. (Frank) Gommans
Netherlands Heart Institute
Theme Animal free innovations
Within theme 4 of focus area 1 (Virus, immunity, immune response and pathogenesis) the ZonMw-program More Knowledge with Fewer Animals and the Dutch Society for the Replacement of Animal Testing (Stichting Proefdiervrij) made extra budget available for the development of the new or wider application of existing animal-free innovations. The ultimate aim is more relevant health(care) research for humans.
- Use of patient-relevant human lung epithelial cell models to study acute and long-term effects of COVID-19
Prof. P.S. (Pieter) Hiemstra
Leiden University Medical Center - Inhalation of Low Molecular Weight Heparins as a prophylaxis to prevent SARS-CoV-2 infection
Prof. T.B.H. (Theo) Geijtenbeek
Amsterdam UMC (location AMC) - Ex vivo models to study tissue-specific features of SARS-CoV-2 infection
Prof. J.M. (Jeffrey) Beekman
University Medical Center Utrecht - Blood Vessels-on-Chip to Understand and Target COVID-19
Dr A.D. (Andries) van der Meer
University of Twente - Employing a physiological microfluidic lung bioreactor to improve understanding of SARS-CoV2 biology and testing of therapeutics
Dr R.J. (Robbert) Rottier
Erasmus MC-Sophia Children’s Hospital
Focus area 2. Care and Prevention
Theme 1: Organisation of care and prevention
- TRACE II: Outcome in patients undergoing postponed elective surgery during the COVID-19 pandemic
Dr J.D. (Dianne) de Korte-de Boer PhD
Maastricht University Medical Center+ - COVID-19 Follow-up care paths and Long-term Outcomes Within the Dutch health care system: a combined rehabilitation, pulmonary, and intensive care perspective (CO-FLOW study)
Dr H.J.G. (Rita) van den Berg-Emons
Erasmus Medical Center - The development of a COVID-19 scoring system for effective and safe triage of patients in the primary care setting.
Dr D.O. (Dennis) Mook-Kanamori MD PhD
Leiden University Medical Center - National and regional coordination in times of scarcity
Prof. J.T. (Taco) van der Vaart
University of Groningen - Changes in the use and organization of care in general practice and out-of-hours services: lessons learned from the COVID-19 pandemic
Dr L.L. (Lilian) Peters
University Medical Center Groningen - A multidisciplinary guide for people with disability using ICT for social contact to mitigate impact of restricted in-person visit policies
Prof. C. (Carlo) Schuengel
VU Amsterdam - Effect of COVID-19 on GP care use by underrepresented patients in deprived neighbourhoods
Dr P.L. (Paul) Kocken
Erasmus University Rotterdam - Improvise, adapt, overwork? Understanding and learning from hospitals' adaptations to COVID-19 and their effects on professional functioning and recovery.
Dr D.D. (Daan) Westra
Maastricht University - Healthcare utilization in primary care during the corona pandemic: a nation-wide population-based study from a patient and healthcare provider perspective
Dr E.I.T. (Evelien) de Schepper
Erasmus Medical Center
Theme 2: Care and prevention for vulnerable citizens
- Population differences in diagnosed covid-19 prevalence in the Netherlands. Which groups are at highest risk?
Dr E.A.L. (Ester) de Jonge
GGD Zuid Holland Zuid - Homeless and COVID-19 – lessons for the future
Prof. M.E.T.C. (Maria) van den Muijsenbergh
Radboud University medical Center - Impact of COVID-19 on children and adolescents with autism spectrum disorder (ASD) and their family
Dr L.P. (Linda) Dekker
Erasmus University Rotterdam - Caring and waving: longitudinal study on the consequences of restrictive COVID-19 measures for relatives of people with intellectual disabilities and their need for support
Dr H.R. (Hennie) Boeije
NIVEL - Consequences of restrictive measures because of COVID-19 outbreak on loneliness and social needs of residents, informal caregivers and volunteers in nursing homes
Dr L.C. (Leonieke) van Boekel MSc
Tilburg University - ICU triage during a crisis: learning from the application of medical and non-medical criteria to patient cases
Dr A.J.M. (Anke) Oerlemans
Radboud University Medical Center
Theme 3: Transmission and epidemiology
- Data-driven Simulation Games for the Evaluation and Prevention of SARS-CoV-2 Transmission in Indoor Public Spaces and the Impact of Changing Compliance to Distancing Measures
Dr Q.A. ten Bosch
Wageningen University & Research - SARS-CoV-2 transmission in secondary schools and the influence of indoor environmental conditions
Prof. P.M. (Philomena) Bluyssen
Delft University of Technology - Towards Evidence-based Social Distancing Policy: Tracking Behavioral Responses to Pandemic Mitigation Measures and Implementation Strategies
Dr M.R. (Marie Rosenkrantz) Lindegaard PhD
Netherlands Institute for the Study of Crime and Law Enforcement - CONTROL (CONtact TRacing OptimaLisation): effectiveness & optimalisation of source investigation and contact tracing to limit spread of SARS-CoV-2
Dr A.A. (Antoinette) Matser
GGD Amsterdam - Serologic surveillance of SARS-CoV-2 during the 2020 pandemic in exposed and unexposed healthcare workers in a tertiary care hospital in Amsterdam (S3 study)
Dr J.J. (Jonne) Sikkens
Amsterdam UMC - location VUmc
Palliative care
- Supporting family members of isolated, life-threatening ill patients with COVID-19 who have been admitted to intensive care
Prof. B. (Bregje) Onwuteaka-Philipsen
Amsterdam UMC, location VUmc - CovId-19 and SOcial isoLATion in dEmentia care (ISOLATE): impact and needs of people with dementia, informal and professional caregivers
Dr M. (Mandy) Visser
Leiden University Medical Center - The impact of the COVID-19 pandemic on death and bereavement (the CO-LIVE project)
Dr I.J. (Ida) Korfage
Erasmus Medical Center
