The COVID-19 pandemic clearly showed the critical interplay between diet-related metabolic diseases and infectious diseases: metabolic diseases such as obesity and type 2 diabetes increased the severity of COVID-19 infection. This emphasised the importance to better understand the role of nutrition in immune function, resilience and dysfunction, and its interplay between diet-related- metabolic and infectious diseases.

Onderwerpen

Proposals should focus on one or both of the following topics:

  • Establishing the cause-and-effect relationship between nutrition, immune function and infectious diseases in the context of diet-related metabolic disorders. Building on existing knowledge to further identify mechanisms of action (including common molecular pathways), projects will:
    • Advance understanding of how nutrition, foods and dietary patterns modulate immune system homeostasis, response (e.g., inflammation), dysregulation and susceptibility to infectious disease across the life course in people with diet-related metabolic diseases.
    • Explore how nutrition may contribute to infectious disease risk in people with diet-related metabolic diseases at various stages including prevention of, severity of, recovery from, and rehabilitation after the infectious disease.
  • Development of innovative food solutions. Proof of principle studies are desired in order to support the development of effective health-improvement strategies and/or food products to promote a healthy immune system in people with diet-related metabolic disease and their application at any stage of the infectious disease process.

Onderdeel van programma

Joint Programming Initiative, Healthy Diet for a Healthy Life (JPI HDHL)

Geplaatst op

15 februari 2022

Deadline

21 april 2022,
16.00 uur

Lees volledige subsidieoproep

Wilt u indienen? De volledige subsidieoproep kunt u via onderstaande link bekijken. Hierin staat alle specifieke informatie over deze oproep.

JPI HDHL: “Nutrition-responsiveness of the immune system: interplay between infectious diseases and diet-related metabolic diseases and the potential for food-based solutions (NUTRIMMUNE)” call (pdf) 546 KB

Purpose of call

The interplay of infectious diseases and diet-related metabolic diseases (i.e. non-communicable and communicable diseases) is of emerging importance globally. With new infectious diseases such as COVID-19, which are more severe and more fatal in individuals with obesity or diabetes, the role of co-morbidities in the susceptibility to and severity of infectious disease has become more visible to the public and policy makers. A better understanding of the complex interplay between nutrition, immune function and resilience (including the inflammation component) and human health will enable society to be better prepared for future pandemics and will improve the burden of metabolic diseases.

The aim of this call is to support transnational, collaborative research projects that gain a better understanding of the interactions between nutrition and immunity within the context of its interplay between infectious diseases and diet-related metabolic diseases

 

Sums available

This call intends to fund top-class transnational and transdisciplinary research consortia in the field of nutrition, infectious diseases and diet-related metabolic diseases.
Relevant research questions may include (but are not limited) scientific evidence for differences in individual susceptibility to and the severity of infectious diseases in people with diet-related metabolic diseases such as obesity or type 2 diabetes. Research should focus on the underlying mechanisms by which nutrition, food composition and/or dietary patterns effect immune function (e.g. both innate and adaptive immune function, and microbiome).
Proof of principle studies are desired in order to support the development of effective diet-related health-improvement strategies health-improvement strategies and/or food products to promote a healthy immune system in people with diet-related metabolic diseases and their application at any stage of the infectious disease process.

 

Requirements

Criteria

  • Research consortia must be transnational
  • Proposals should focus on the interplay between nutrition, infectious diseases and diet-related metabolic diseases.
  • Proposals should focus on one or more crucial phase(s) and/or age groups throughout the lifespan.

For a more elaborate explanation of the requirements, we kindly refer to the call text

Eligible candidates

The Netherlands (ZonMw and Health~Holland) is participating in this call. Dutch researcher organisations such as universities and academic hospitals can apply for funding.
The Dutch consortium consists of at least one research organisation and one for-profit enteprise.
Co-funding by a for-profit enterprise is a condition for Dutch applicants to be eligible.

Criteria transnational consortium:

  • Minimum of 3 partners from 3 different participating countries.
  • No more than 2 partners of one country.
  • Maximum of 8 partners (including maximum of 2 collaborators)

Budget

Total budget available for the Netherlands is €1.750.000, to fund approximately 4 proposals with Dutch participation.

 

Submit application

You may submit your application through the JPI HDHL Electronic Submission System until 21 April 2022 at 16:00 CEST. No other means of submission will be accepted.

Download all information

The call text can be downloaded as a pdf and contains all detailed information about this call.

JPI HDHL: “Nutrition-responsiveness of the immune system: interplay between infectious diseases and diet-related metabolic diseases and the potential for food-based solutions (NUTRIMMUNE)” call (pdf) 546 KB

Contact

Please contact us with any questions that are not covered in the FAQs. For general queries, please contact Dr. Wilke van Ansem. If you have any technical questions ZonMw’s online application system please contact the service desk.

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