The aim of the project is to arrive at reasoned decision concerning a pre conceptional screening programme for cystic fibrosis carriers. On the basis of the results of the project a decision can be drawn whether a nationwide screening programme should be started or not. Furthermore a choice for a specific strategy can be made. Recruitment strategies, tested on feasibility in an ongoing pilot study, will be considered. The focus will be on possibilities and barriers to be expected for a nationwide screening programme. First an inventory will be made with providers potentially involved in the screening programme and persons in the target groups. Data will be gathered from representative samples. Secondly the relevant national organisations (decision makers, financiers and others) will be asked to take part in a Delphi procedure to develop an implementation plan.