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Cost-effectiveness analysis of screening for peripheral arterial occlusive disease and subsequent risk factor modification for the prevention of myocardial infarction and stroke: A computer simulation study.

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Samenvatting van de aanvraag

Whereas secondary prevention of cardiovascular events through risk factor modification in patients with known coronary or carotid artery disease is recognized as cost-effective, risk factor interventions in low risk groups have shown only small benefits and are extremely expensive. Targeting primary prevention to individuals at a high risk for an event could, however, potentially be cost-effective. Patients with peripheral arterial occlusive disease, either symptomatic or asymptomatic, are at a high risk for a myocardial infarction and stroke. The disease can be diagnosed non-invasively and inexpensively with the measurement of an ankle-brachial index (ratio of the systolic ankle and arm pressure). Purpose of the proposed computer simulation study is to evaluate the relative cost-effectiveness of various screening strategies for peripheral arterial occlusive disease with subsequent intensive risk factor modification in those individuals identified to have the disease.

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Projectnummer:
22000067
Looptijd: 100%
Looptijd: 100 %
2000
2002
Onderdeel van programma:
Projectleider en penvoerder:
Prof. dr. M.G.M. Hunink
Verantwoordelijke organisatie:
Erasmus MC