PM-KIDNEY: Pollution is the Motor of premature ageing of the KIDNEY

Lopend (juli 2020 - juli 2025)

Aging of kidneys Premature renal ageing is a risk factor for cardio-vascular adverse events, the development of chronic kidney disease (CKD) and progression towards end stage renal disease (ESRD). ESRD is associated with low quality of life, high morbidity and mortality, and tremendous health care expenses. Air pollution (PM2.5) increases risk on Chronic Kidney Disease The incidence of ESRD...

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The role of DNA damage and mitochondrial function in vascular, immune and neurological ageing

Lopend (juni 2020 - juni 2025)

Age-related vascular diseases can be prevented The world population is getting older and older. Unfortunately this increased life expectancy is generally associated by so-called age-related vascular diseases, such as dementia, heart infarct and stroke. However, these age-related chronic disorders can be delayed or even prevented by interference with common critical mechanisms underlying these...

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