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Sensing in Surgery

Projectomschrijving

Tijdens chirurgische interventies is kennis over zachte weefsel van groot belang om te voorkomen dat gezond weefsel onnodig wordt beschadigd, maar ook om ervoor te zorgen dat er geen tumorweefsel achterblijft in het lichaam. De te ontwikkelen instrumenten hebben ten doel te voorkomen dat 1) te hoge krachten op het weefsel ontstaan, dat kan leiden tot pijn, of erger, 2) weefselbeschadiging, en 3) dat tumorweefsel niet volledig wordt verwijderd. Van de instrumenten die met behulp van slimme technieken, krachten en optische eigenschappen van weefsel tijdens een chirurgische ingreep kunnen meten, bestaan al prototypes. Samen met clinici in verschillende ziekenhuizen en samen met (spin-off) bedrijven zullen deze instrumenten met sensingmogelijkheden door worden ontwikkeld, zodat ze bruikbaar worden in de klinische praktijk.

Producten

Titel: Sara Azizian won Best Oral Presentation award during the 32st The International Conference of the Society for Medical Innovation and Technology (SMIT), Oslo, Norway, 2022.
Titel: New method in safe tissue handling; a magnetically balanced compliant laparoscopic grasper
Auteur: Jan Willem Klok et al.
Titel: Design of a 3D-printed, low-cost, modular hip implant device for soft tissue tension and motion tracking during total hip arthroplasty
Auteur: Jonathan Wei et al.
Titel: Smart electrosurgical knife for real-time tumor border detection during breast conserving surgery .” 8th Dutch Bio-Medical Engineering-2021.
Auteur: Sara Azizian Amiri, Jenny Dankelman, and Benno H. W. Hendriks
Titel: Compliant mechanisms can potentially prevent soft tissue trauma in laparoscopic surgery
Auteur: Jan Willem Klok et al.
Titel: Smart Electrosurgical Knife with Diffuse Reflectance Spectroscopy for Real-time Oncological Guidance,
Auteur: Sara Azizian Amiri, Carlijn M. Van Gent, Jenny Dankelman, and Benno H. W. Hendriks
Link: http://smit2019.com/
Titel: Optical Knife for real-time tumor detection.
Auteur: Sara Azizian Amiri, Jenny Dankelman, and Benno H. W. Hendriks
Link: https://smit.gyroconference.no/
Titel: Design of a statically balanced compliant laparoscopic grasper
Auteur: Jan-Willem Klok et al.
Link: http://smit2019.com/
Titel: Smart electrosurgical knife for real-time tumor border detection during lumpectomy surgery on a realistic breast phantom” 32st The International Conference of the Society for Medical Innovation and Technology (SMIT), Chicago, USA, 2020.
Auteur: Sara Azizian Amiri, Jenny Dankelman, and Benno H. W. Hendriks
Titel: 3DOF instrumented implant for force and orientation sensing of soft tissues
Auteur: Jonathan Wei et. al.
Titel: The influence of simulating cyclic diaphragm movement on acquisition of basic laparoscopic skills training with an actuated training platform
Auteur: Jan-Willem Klok et al.
Titel: New method in safe tissue handling; a magnetically balanced compliant laparoscopic grasper
Auteur: Jan-Willem Klok et al.
Titel: Tissue-mimicking phantom materials with tunable optical properties suitable for assessment of diffuse reflectance spectroscopy during electrosurgery
Auteur: Sara Azizian Amiri, Pieter Van Berckel, Marco Lai, Jenny Dankelman, and Benno H. W. Hendriks
Magazine: Biomedical Optics Express Vol. 13, Issue 5
Begin- en eindpagina:
Link: https://opg.optica.org/boe/fulltext.cfm?uri=boe-13-5-2616&id=471030
Titel: Design of an Affordable, Modular Implant Device for Soft Tissue Tension Assessment and Range of Motion Tracking During Total Hip Arthroplasty
Auteur: Jonathan C. J. Wei, Bryan Blaauw, Dieter G. M. Van Der Pol, Mauricio Cruz Saldívar, Chung-Feng Lai, Jenny Dankelman, and Tim Horeman
Magazine: IEEE Journal of Translational Engineering in Health and Medicine
Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9191686/
Titel: Design and In Vitro Validation of an Orthopaedic Drill Guide for Femoral Stem Revision in Total Hip Arthroplasty
Auteur: Jan-Willem Klok; Jessica Groenewegen; Olivier Temmermans; Niels Van Straten; Bart Van Straten; Jenny Dankelman; Tim Horeman
Magazine: IEEE Journal of Translational Engineering in Health and Medicine
Begin- en eindpagina:
Link: https://ieeexplore.ieee.org/abstract/document/10433182
Titel: Intraoperative tumor margin assessment using diffuse reflectance spectroscopy: the effect of electrosurgery on tissue discrimination using ex vivo animal tissue models
Auteur: Sara Azizian Amiri, Carlijn M. Van Gent, Jenny Dankelman, and Benno H. W. Hendriks
Magazine: Biomedical Optics Express Vol. 11, Issue 5, pp. 2402-2415 (2020)
Begin- en eindpagina:
Link: https://opg.optica.org/boe/fulltext.cfm?uri=boe-11-5-2402&id=429811
Titel: Heterogeneous Breast Phantoms with Tunable Optical Properties suitable for Tumor Detection During Electrosurgery.
Auteur: S. Azizian Amiri, Pieter van Berckel, Marco Lai, J. Dankelman, B.H.W. Hendriks
Magazine: Biomedical Optics Express
Link: https://opg.optica.org/boe/fulltext.cfm?uri=boe-13-5-2616&id=471030
Titel: Electrosurgical knife equipped with diffused reflectance spectroscopy sensing for tumor margin detection during breast conserving surgery: a phantom study.
Auteur: Azizian Amiri, Sara, van Berckel, Pieter, Dankelman, Jenny, Hendriks, Benno H.
Magazine: Proceedings of SPIE
Link: https://www.osapublishing.org/boe/fulltext.cfm?uri=boe-11-5-2402&id=429811
Titel: Using Acoustic Vibrations as a Method for Implant Insertion Assessment in Total Hip Arthroplasty. Sensors 2022, 22, 1609. https://doi.org/10.3390/s22041609
Auteur: Wei, J.C.J.; Crezee, W.H.A.; Jongeneel, H.; De Haas, T.S.A.; Kool, W.L.A.; Blaauw, B.J.; Dankelman, J.; Horeman, T.
Magazine: Sensors 2022, 22, 1609.
Begin- en eindpagina:
Link: https://www.mdpi.com/1424-8220/22/4/1609
Titel: Design of an Affordable, Modular Implant Device for Soft Tissue Tension Assessment and Range of Motion Tracking During Total Hip Arthroplasty
Auteur: Wei, J.C.; Blaauw, Bryan; van der Pol, D.G.M.; Cruz Saldivar, M.; Lai, C.; Dankelman, J.; Horeman, T
Magazine: IEEE Journal of Translational Engineering in Health and Medicine
Begin- en eindpagina:
Link: https://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=9773350
Titel: Enhancing Intraoperative Tissue Identification: Investigating a Smart Electrosurgical Knife's Functionality During Electrosurgery
Auteur: Sara Azizian Amiri; Jenny Dankelman; Benno H. W. Hendriks
Magazine: IEEE Transactions on Biomedical Engineering
Begin- en eindpagina:
Link: https://ieeexplore.ieee.org/abstract/document/10420437
Titel: Electrosurgical knife equipped with diffused reflectance spectroscopy sensing for tumor margin detection during breast conserving surgery: a phantom study
Auteur: Sara Azizian Amiri, Pieter van Berckel, Jenny Dankelman, Benno H. W. Hendriks
Magazine: SPIE.digital libary, Proceedings Volume 11631, Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XIX; 1163110 (2021)
Begin- en eindpagina:
Link: https://www.spiedigitallibrary.org/conference-proceedings-of-spie/11631/1163110/Electrosurgical-knife-equipped-with-diffused-reflectance-spectroscopy-sensing-for-tumor/10.1117/12.2576636.full
Titel: Design and Evaluation of a Balanced Compliant Laparoscopic Grasper
Auteur: Jan-Willem Klok; Roelf Postema; Asþor T. Steinþorsson; Jenny Dankelman; Tim Horeman
Magazine: IEEE Journal of Translational Engineering in Health and Medicine, vol. 11, pp. 451-459, 2023,
Begin- en eindpagina:
Link: https://ieeexplore.ieee.org/document/10172011
Titel: Using Acoustic Vibrations as a Method for Implant Insertion Assessment in Total Hip Arthroplasty
Auteur: Wei, J.C.J.; Crezee, W.H.A.; Jongeneel, H.; De Haas, T.S.A.; Kool, W.L.A.; Blaauw, B.J.; Dankelman, J.; Horeman, T.
Magazine: Sensors
Link: https://doi.org/10.3390/s22041609
Titel: Intraoperative tumor margin assessment using diffuse reflectance spectroscopy: the effect of electrosurgery on tissue discrimination using ex vivo animal tissue models
Auteur: Sara Azizian Amiri, Carlijn M. Van Gent, Jenny Dankelman, and Benno H. W. Hendriks
Magazine: Biomedical Optics Express
Titel: Patent Nederlandse octrooiaanvrage nr. 2024695; Force sensor; Uw ref. OCT-19-115; Onze ref. 019101 NL-PD-VB/yt
Auteur: T. Horeman

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Samenvatting van de aanvraag

Sensing in Surgery (IMDI CoRes-NIMIT) Surgery experiences challenges recognized to be solved by novel sensing technology. During surgical procedures soft tissues need to be dissected very accurately to reduce unnecessary tissue damage, tumour spread and pain. Grasping delicate soft tissue and connecting soft tissue structures safely require precise force and tension sensing. Moreover, dissecting tissues accurately, while preventing cutting through critical structures like tumours and nerves, requires sensing. The amount of sensing information is currently limited. Within the Sensing in Surgery program we aim to join forces to bring existing soft tissue sensing technology in the clinic and provide surgeon with extra sensing information so that tissue damage, incomplete tumour resection, and pain can be largely reduced. The challenges of the Sensing in Surgery program are: (S1) Preventing pain by sensing soft tissue tension around the hip, (S2) Preventing tissue damage by sensing soft tissue while pinching, and (S3) Preventing incomplete tumour resection by sensing tumour margins during the resection. To enhance surgical sensing and bring the sensing instruments through the ‘valley of death’, we will join the translation/valorisation experience of research institutes (engineering/ clinical), hospitals, small spin-off and large companies, and together bring innovative surgical sensing instruments into clinical practice.

Onderwerpen

Kenmerken

Projectnummer:
104006002
Looptijd: 100%
Looptijd: 100 %
2018
2024
Onderdeel van programma:
Gerelateerde subsidieronde:
Projectleider en penvoerder:
prof. dr. J. Dankelman
Verantwoordelijke organisatie:
Technische Universiteit Delft