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The aim of the CHILI study is to develop and determine the effectiveness of an illness focussed intervention (GP-parent information exchange tool) and a disease focussed intervention (CRP point of care test) on the management (antibiotic prescribing, antipyretic use, compliance, (re)consulting, referral and complications) of children presenting with fever in Dutch general practice (GP) out-of-hours services, as well as on relevant parental outcomes (satisfaction, worries and enablement). The study will consist of five workpackages (WP):

 

WP1:Parental views and experiences with childhood fever

Nationwide survey among 1000 parents with young children on parental knowledge, attitudes and practices concerning fever in young children

 

WP2:Stakeholders’ views and attitudes towards management of children with fever

Focusgroups with GPs, triage nurses, pharmacologists and parents of children having consulted out-of-hours with a febrile illness.

 

WP3:GPs use of a doctor-parent information-exchange tool in the management of children with fever

Stepped wedge design to evaluate of the effect of GP use of the interactive GP-parent tool within consultations in young children consulting with febrile illness in the GP out-of-hours services on: antibiotic prescriptions,(re-)consultations, intention to re-consult, knowledge about antipyretics and fever, satisfaction with care, patient enablement scored by parents, serious adverse events.

 

WP4:CRP point of care test in the management of children with fever

Individually randomised trial (RCT) evaluating the effectiveness of using CRP point of care testing in children 3 months to 12 years old consulting with febrile illness in the GP out-of-hours services, on antibiotic prescribing and several other outcomes (see WP3).

 

WP5:Dissemination and education

Disseminating results and developing educational tools to bring results to clinicians, parents and stakeholders (out-of-hours services, health insurances, policymakers).

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