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GLYCOTalk: Unraveling the biological function of streptococcal polysaccharides in host-pathogen interaction

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Titel: Interplay between bacterial surface glycans and host immunity: implications for new therapies
Auteur: Nina M. van Sorge
Titel: Interplay between bacterial surface glycans and host immunity
Auteur: Nina M. van Sorge
Titel: Streptococcal Lancefield antigens harbor virulence epitopes
Auteur: Nina M. van Sorge, Jason N. Cole, C. Hilvering, Ramy K. Aziz, Patrick M. Schlievert, Victor Nizet
Titel: Transport of rhamnose polysaccharides in Streptococci
Auteur: Samantha van der Beek, Nina van Sorge
Titel: The Group A Streptococcus cell wall carbohydrate: a virulence factor and universal vaccine candidate
Auteur: Nina M. van Sorge
Titel: Functional and structural characterization of rhamnose biosynthesis enzymes in Group A Streptococcus
Auteur: Samantha van der Beek, Nina van Sorge
Titel: Immune evasion by Staphylococcus aureus by targeting lectin receptors
Auteur: Rob van Dalen, Nina M. van Sorge
Titel: Glycosylated cell wall structures at the host-pathogen interface
Auteur: NM van Sorge
Link: https://secure.faseb.org/src-programs/11780.pdf
Titel: Functional and structural characterization of rhamnose biosynthesis enzymes in Group A Streptococcus
Auteur: Samantha van der Beek, Nina van Sorge
Titel: GacA is Essential for Group A Streptococcus and Defines a New Class of Monomeric dTDP-4-dehydrorhamnose Reductases
Titel: Streptococcal surface glycans at the host-pathogen interface
Auteur: NM van Sorge
Titel: Glycosylated cell wall structures at the host-pathogen interface
Auteur: NM van Sorge
Titel: Human Langerin interacts with a conserved glycol modification of Staphylococcus aureus wall teichoic acid
Auteur: Rob van Dalen, Matevž Rumpret, Christoph Rademacher, Andreas Peschel, Jos A. van Strijp, Nina M. van Sorge
Auteur: Samantha L. van der Beek,Yoann Le Breton, Andrew T. Ferenbach, Daan M.F. van Aalten, Iva Navratilova, Kevin McIver, Nina M. van Sorge and Helge C. Dorfmueller
Titel: Functional and structural characterization of rhamnose biosynthesis pathway enzymes in Group A Streptococcus
Auteur: Samantha L. van der Beek, Yoann Le Breton, Andrew T. Ferenbach, Daan M.F. van Aalten, Iva Navratilova, Kevin McIver, Helge C. Dorfmueller, and Nina M. van Sorge
Titel: Streptococcal glycans: of virulence factors and vaccines
Titel: Glycosylated cell wall structures at the host-pathogen interface
Auteur: NM van Sorge
Titel: Glycosylated cell wall structures at the host-pathogen interface
Auteur: NM van Sorge
Titel: Streptococcal dTDP-L-rhamnose biosynthesis enzymes: functional characterization and lead compound identification
Auteur: van der Beek, Samantha L., Zorzoli, Azul, Çanak, Ebru, Chapman, Robert N., Lucas, Kieron, Meyer, Benjamin H., Evangelopoulos, Dimitrios, de Carvalho, Luiz Pedro S., Boons, Geert-Jan, Dorfmueller, Helge C., van Sorge, Nina M.
Magazine: Molecular Microbiology
Titel: Langerhans Cells Sense Staphylococcus aureus Wall Teichoic Acid through Langerin To Induce Inflammatory Responses
Auteur: van Dalen, Rob, De La Cruz Diaz, Jacinto S., Rumpret, Matevž, Fuchsberger, Felix F., van Teijlingen, Nienke H., Hanske, Jonas, Rademacher, Christoph, Geijtenbeek, Teunis B. H., van Strijp, Jos A. G., Weidenmaier, Christopher, Peschel, Andreas, Kaplan, Daniel H., van Sorge, Nina M.
Magazine: mBio
Titel: Defining Host Responses during Systemic Bacterial Infection through Construction of a Murine Organ Proteome Atlas
Auteur: Lapek, John D., Mills, Robert H., Wozniak, Jacob M., Campeau, Anaamika, Fang, Ronnie H., Wei, Xiaoli, van de Groep, Kirsten, Perez-Lopez, Araceli, van Sorge, Nina M., Raffatellu, Manuela, Knight, Rob, Zhang, Liangfang, Gonzalez, David J.
Magazine: Cell Systems
Link: https://www.ncbi.nlm.nih.gov/pubmed/29778837
Titel: Discovery of glycerol phosphate modification on streptococcal rhamnose polysaccharides
Auteur: Edgar, Rebecca J., van Hensbergen, Vincent P., Ruda, Alessandro, Turner, Andrew G., Deng, Pan, Le Breton, Yoann, El-Sayed, Najib M., Belew, Ashton T., McIver, Kevin S., McEwan, Alastair G., Morris, Andrew J., Lambeau, Gérard, Walker, Mark J., Rush, Jeffrey S., Korotkov, Konstantin V., Widmalm, Göran, van Sorge, Nina M., Korotkova, Natalia
Magazine: Nature Chemical Biology
Titel: Staphylococcus aureus wall teichoic acid is a pathogen-associated molecular pattern that is recognized by langerin (CD207) on skin Langerhans cells
Auteur: van Dalen, Rob, De La Cruz Diaz, Jacinto S, Rumpret, Matevž, Fuchsberger, Felix F, van Teijlingen, Nienke H, Hanske, Jonas, Rademacher, Christoph, Geijtenbeek, Teunis B.H., Van Strijp, Jos A. G., Weidenmaier, Christopher, Peschel, Andreas, Kaplan, Daniel H, van Sorge, Nina M
Magazine: BioRxiv
Link: https://www.biorxiv.org/content/biorxiv/early/2018/10/17/238469.full.pdf
Titel: Women in Translational Medicine: Tools to Break the Glass Ceiling
Auteur: Bots, Sophie H., Zuidgeest, Mira G. P., Gohar, Aisha, Eikendal, Anouk L. M., Petrelli, Alessandra, van Os-Medendorp, Harmieke, van der Schaaf, Marieke F., van Sorge, Nina M., van Wijk, Myriam, Middendorp, Sabine, Speksnijder, Caroline M., Klipstein-Grobusch, Kerstin, Seyfert-Margolis, Vicky, Mollema, Esther, van Wijk, Femke, den Ruijter, Hester M.
Magazine: Frontiers in Medicine
Titel: Genetic insight into zinc and antimicrobial toxicity uncovers a glycerol phosphate modification on streptococcal rhamnose polysaccharides
Auteur: Edgar, Rebecca J., van Hensbergen, Vincent P., Ruda, Alessandro, Turner, Andrew G., Deng, Pan, Le Breton, Yoann, El-Sayed, Najib M., Belew, Ashton T., McIver, Kevin S., McEwan, Alistair G., Morris, Andrew J., Lambeau, Gerard, Walker, Mark J., Rush, Jeffrey S., Korotkov, Konstantin V., Widmalm, Goran, van Sorge, Nina M., Korotkova, Natalia
Magazine: BioRxiv
Titel: Bacterial glycobiology: rhamnose-containing cell wall polysaccharides in Gram-positive bacteria
Auteur: Mistou, Michel-Yves, Sutcliffe, Iain C., van Sorge, Nina M.
Magazine: FEMS Microbiology Reviews
Link: http://femsre.oxfordjournals.org/content/early/2016/03/13/femsre.fuw006.long
Titel: Groep A-streptokokken: update over pathogenese en vaccinontwikkeling
Auteur: N.M. van Sorge
Magazine: Tijdschrift voor Infectieziekten
Titel: Streptococcal dTDP-L-rhamnose biosynthesis enzymes: functional characterization and lead compound identification
Auteur: van der Beek, Samantha L, Zorzoli, Azul, Çanak, Ebru, Chapman, Robert N, Meyer, Benjamin H, Boons, Geert-Jan P.H., Dorfmueller, Helge C, van Sorge, Nina M
Magazine: BioRxiv
Titel: A Specific, Glycomimetic Langerin Ligand for Human Langerhans Cell Targeting
Auteur: Wamhoff, Eike-Christian, Schulze, Jessica, Bellmann, Lydia, Rentzsch, Mareike, Bachem, Gunnar, Fuchsberger, Felix F., Rademacher, Juliane, Hermann, Martin, Del Frari, Barbara, van Dalen, Rob, Hartmann, David, van Sorge, Nina M., Seitz, Oliver, Stoitzner, Patrizia, Rademacher, Christoph
Magazine: ACS Central Science
Titel: Virulence Role of the GlcNAc Side Chain of the Lancefield Cell Wall Carbohydrate Antigen in Non-M1-Serotype Group A Streptococcus
Auteur: A. Henningham, M.R. Davies, S. Uchiyama, N. M. van Sorge, S. Lund, K.T. Chen, M.J. Walker, J.N. Cole, and V. Nizet
Magazine: mBio
Titel: Lipoteichoic acid anchor triggers Mincle to drive protective immunity against invasive group A Streptococcus infection
Auteur: Imai, Takashi, Matsumura, Takayuki, Mayer-Lambertz, Sabine, Wells, Christine A., Ishikawa, Eri, Butcher, Suzanne K., Barnett, Timothy C., Walker, Mark J., Imamura, Akihiro, Ishida, Hideharu, Ikebe, Tadayoshi, Miyamoto, Tomofumi, Ato, Manabu, Ohga, Shouichi, Lepenies, Bernd, van Sorge, Nina M., Yamasaki, Sho
Magazine: Proceedings of the National Academy of Sciences USA
Titel: The molecular mechanism ofN-acetylglucosamine side-chain attachment to the Lancefield group A carbohydrate inStreptococcus pyogenes
Auteur: Rush, Jeffrey S., Edgar, Rebecca J., Deng, Pan, Chen, Jing, Zhu, Haining, van Sorge, Nina M., Morris, Andrew J., Korotkov, Konstantin V., Korotkova, Natalia
Magazine: Journal of Biological Chemistry
Link: http://www.jbc.org/content/292/47/19441
Titel: Streptococcal Lancefield polysaccharides are critical cell wall determinants for human Group IIA secreted phospholipase A2 to exert its bactericidal effects
Auteur: van Hensbergen, Vincent P., Movert, Elin, de Maat, Vincent, Lüchtenborg, Christian, Le Breton, Yoann, Lambeau, Gérard, Payré, Christine, Henningham, Anna, Nizet, Victor, van Strijp, Jos A. G., Brügger, Britta, Carlsson, Fredric, McIver, Kevin S., van Sorge, Nina M.
Magazine: PLoS Pathogens
Titel: GacA is essential for Group A Streptococcus and defines a new class of monomeric dTDP-4-dehydrorhamnose reductases (RmlD)
Auteur: S.L. van der Beek, Y. Le Breton, A.T. Ferenbach, R.N. Chapman, D.M.F. van Aalten, I. Navratilova, G-J. Boons, K. McIver, N.M. van Sorge, H.C. Dorfmueller.
Magazine: Molecular Microbiology
Titel: Group IIA-Secreted Phospholipase A2 in Human Serum Kills Commensal but Not Clinical Enterococcus faecium Isolates
Auteur: Paganelli, Fernanda L., Leavis, Helen L., He, Samantha, van Sorge, Nina M., Payré, Christine, Lambeau, Gérard, Willems, Rob J. L., Rooijakkers, Suzan H. M.
Magazine: Infection and Immunity
Titel: A Common Genetic Variation in Langerin (CD207) Compromises Cellular Uptake of Staphylococcus aureus
Auteur: van Dalen, Rob, Fuchsberger, Felix F., Rademacher, Christoph, van Strijp, Jos A.G., van Sorge, Nina M.
Magazine: Journal of Innate Immunity
Titel: The art of phospholipase A2-IIA
Auteur: Vincent P. van Hensbergen
Titel: Making and Breaking Streptococcal Rhamnose Polysaccharides
Auteur: Samantha L. van der Beek
Titel: Immune recognition of Staphylococcus aureus wall teichoic acid
Auteur: Rob van Dalen

Onderwerpen

Kenmerken

Projectnummer:
91713303
Looptijd: 100%
Looptijd: 100 %
2013
2019
Gerelateerde subsidieronde:
Projectleider en penvoerder:
Dr. N.M. van Sorge
Verantwoordelijke organisatie:
University Medical Center Utrecht