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Renal multilamellar bodies: new players in body lipid metabolism

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Titel: A critical Role for Nlrp3 on Renal Inflammation and Fibrosis in a Model fo Diet-Induced Renal Failure
Titel: The NLRP3 inflammasome: downstream or upstream of renal lipotoxicity?
Auteur: Elena Rampanelli, Peter Ochodnicky, Evelyn Orsó, Sandrine Florquin, Gerd Schmitz, Jaklien C. Leemans
Titel: NLRP3 inflammasome endorses phospholipid accumulation and mitochondrial dysfunction in epithelial cells upon overnutrition.
Auteur: Elena Rampanelli, Evelyn Orsó, Gerhard Liebisch, Sandrine Florquin, Gerd Schmitz, and Jaklien C. Leemans.
Titel: Renal dysfunction and Metabolic Syndrome: the Chicken or the Egg?
Auteur: 12. Elena Rampanelli, Peter Ochodnicky, Evelyn Orsó, Sandrine Florquin, Gerd Schmitz, Jaklien C. Leemans
Titel: NLRX1 contributes to metabolic syndrome by dampening mitochondrial oxidative phosphorylation.
Auteur: Kors L, Rampanelli E, Stokman G, Butter LM, Held NM, Claessen N, Larsen PWB, Verheij J, Zuurbier CJ, Liebisch G, Schmitz G, Girardin SE, Florquin S, Houtkooper RH, Leemans JC.
Titel: NLRX1 attenuates renal fibrosis after unilateral ureteral obstruction in mice
Auteur: Lotte Kors, Geurt Stokman, Loes Butter, Dominique A.J. Garnier, Stephen E. Girardin, Sandrine Florquin and Jaklien C. Leemans
Titel: NLRX1 deficiency prevents diet-induced hepatic steatosis by promoting mitochondrial oxidative phosphorylation in hepatocytes
Auteur: Kors L, Rampanelli E, Stokman G, Butter LM, Held NM, Claessen N, Larsen PWB, Verheij J, Zuurbier CJ, Liebisch G, Schmitz G, Girardin SE, Florquin S, Houtkooper RH, Leemans JC.
Titel: Cholesterol-enriched diet provokes pathological alterations in kidneys with traits typical of lysosomal storage diseases
Auteur: 2. Rampanelli E, Ochodnicky P, Vissers JP, Butter LM, Claessen N, Calcagni A, Kors L, Gethings LA, Bakker SJ, de Borst MH, Navis GJ, Liebisch G, Speijer D, van den Bergh Weerman MA, Jung B, Aten J, Steenbergen E, Schmitz G, Ballabio A, Florquin S, Aerts JM, Leemans JC.
Titel: Proteomic characterisation of renal multilammelar bodies induced by kidney metabolic injury
Auteur: Peter Ochodnicky, Lee A Gethings, Leroy B Martin, Johannes PC Vissers, Johannes MFG Aerts, Jaklien C Leemans
Titel: Deletion of NLRX1 increases fatty acid metabolism and prevents diet-induced hepatic steatosis and metabolic syndrome
Auteur: Kors, Lotte, Rampanelli, Elena, Stokman, Geurt, Butter, Loes M., Held, Ntsiki M., Claessen, Nike, Larsen, Per W.B., Verheij, Joanne, Zuurbier, Coert J., Liebisch, Gerhard, Schmitz, Gerd, Girardin, Stephen E., Florquin, Sandrine, Houtkooper, Riekelt H., Leemans, Jaklien C.
Magazine: BioChim BioPhys ACta
Titel: NLRX1 is not involved in the host defense against Escherichia coli induced pyelonephritis
Auteur: Kors, Lotte, Butter, Loes M., Claessen, Nike, Teske, Gwendoline J.D., Girardin, Stephen E., Florquin, Sandrine, Leemans, Jaklien C.
Magazine: F1000 Research
Titel: Metabolic injury-induced NLRP3 inflammasome activation dampens phospholipid degradation
Auteur: Rampanelli, Elena, Orsó, Evelyn, Ochodnicky, Peter, Liebisch, Gerhard, Bakker, Pieter J., Claessen, Nike, Butter, Loes M., van den Bergh Weerman, Marius A., Florquin, Sandrine, Schmitz, Gerd, Leemans, Jaklien C.
Magazine: Scientific Reports
Titel: Deletion of NLRX1 increases fatty acid metabolism and prevents diet-induced hepatic steatosis and metabolic syndrome
Auteur: Kors, Lotte, Rampanelli, Elena, Stokman, Geurt, Butter, Loes M., Held, Ntsiki M., Claessen, Nike, Larsen, Per W.B., Verheij, Joanne, Zuurbier, Coert J., Liebisch, Gerhard, Schmitz, Gerd, Girardin, Stephen E., Florquin, Sandrine, Houtkooper, Riekelt H., Leemans, Jaklien C.
Magazine: Biochimica et Biophysica Acta - Molecular Basis of Disease
Titel: Pattern recognition receptors and the inflammasome in kidney disease
Auteur: Leemans, Jaklien C., Kors, Lotte, Anders, Hans-Joachim, Florquin, Sandrine
Magazine: Nature Reviews Nephrology
Titel: Modelling TFE renal cell carcinoma in mice reveals a critical role of WNT signaling
Auteur: Calcagnì, Alessia, kors, Lotte, Verschuren, Eric, De Cegli, Rossella, Zampelli, Nicolina, Nusco, Edoardo, Confalonieri, Stefano, Bertalot, Giovanni, Pece, Salvatore, Settembre, Carmine, Malouf, Gabriel G, Leemans, Jaklien C, de Heer, Emile, Salvatore, Marco, Peters, Dorien JM, Di Fiore, Pier Paolo, Ballabio, Andrea
Magazine: eLife
Titel: Nlrp3 is a key modulator of diet-induced nephropathy and renal cholesterol accumulation
Auteur: Bakker, Pieter J., Butter, Loes M., Kors, Lotte, Teske, Gwendoline J.D., Aten, Jan, Sutterwala, Fayyaz S., Florquin, Sandrine, Leemans, Jaklien C.
Magazine: Kidney International
Titel: Excessive dietary lipid intake provokes an acquired form of lysosomal lipid storage disease in the kidney
Auteur: Rampanelli, Elena, Ochodnicky, Peter, Vissers, Johannes PC, Butter, Loes M, Claessen, Nike, Calcagni, Alessia, Kors, Lotte, Gethings, Lee A, Bakker, Stephan JL, de Borst, Martin H, Navis, Gerjan J, Liebisch, Gerhard, Speijer, Dave, van den Bergh Weerman, Marius A, Jung, Bettina, Aten, Jan, Steenbergen, Eric, Schmitz, Gerd, Ballabio, Andrea, Florquin, Sandrine, Aerts, Johannes MFG, Leemans, Jaklien C
Magazine: Journal of Pathology
Titel: Combining streptozotocin and unilateral nephrectomy is an effective method for inducing experimental diabetic nephropathy in the ‘resistant’ C57Bl/6J mouse strain
Auteur: Uil, Melissa, Scantlebery, Angelique M. L., Butter, Loes M., Larsen, Per W. B., de Boer, Onno J., Leemans, Jaklien C., Florquin, Sandrine, Roelofs, Joris J. T. H.
Magazine: Scientific Reports
Titel: NLRX1 dampens oxidative stress and apoptosis in tissue injury via control of mitochondrial activity
Auteur: Stokman, Geurt, Kors, Lotte, Bakker, Pieter J., Rampanelli, Elena, Claessen, Nike, Teske, Gwendoline J.D., Butter, Loes, van Andel, Harmen, van den Bergh Weerman, Marius A., Larsen, Per W.B., Dessing, Mark C., Zuurbier, Coert J., Girardin, Stephen E., Florquin, Sandrine, Leemans, Jaklien C.
Magazine: Journal of Experimental Medicine
Titel: NLRX1 does not play a role in diabetes nor the development of diabetic nephropathy induced by multiple low doses of streptozotocin.
Auteur: Scantlebery AML, Uil M, Butter LM, Poelman R, Claessen N, Girardin SE, Florquin S, Roelofs JJTH, Leemans JC.
Magazine: PLoS ONE

Onderwerpen

Kenmerken

Projectnummer:
91712386
Looptijd: 100%
Looptijd: 100 %
2012
2019
Gerelateerde subsidieronde:
Projectleider en penvoerder:
Dr. J.C. Leemans
Verantwoordelijke organisatie:
Amsterdam UMC - locatie AMC