Titel: Nicotiana benthamiana a-galactosidase A1.1 can functionally complement human a-galactosidase A deficiency associated with Fabry disease
Auteur(s): Kassiani Kytidou, Jules Beekwilder, Marta Artola, Eline van Meel, Ruud H. P. Wilbers, Geri F. Moolenaar, Nora Goosen, Maria J. Ferraz, Rebecca Katzy, Patrick Voskamp, Bogdan I. Florea, Cornelis H. Hokke, Herman S. Overkleeft, Arjen Schots, Dirk Bosch, Navraj Pannu and Johannes M. F. G. Aerts
Tijdschrift: Journal of Biological Chemistry
Start- en eindpagina: 10042 - 10058
Publicatiedatum: 29-06-2018
DOI: 10.1074/jbc.RA118.001774
Titel: Functional characterization of Schistosoma mansoni fucosyltransferases in Nicotiana benthamiana plants
Auteur(s): Kim van Noort, Dieu-Linh Nguyen, Verena Kriechbaumer, Chris Hawes, Cornelis H. Hokke, Arjen Schots & Ruud H. P. Wilbers
Tijdschrift: Scientific Reports
Start- en eindpagina: 18528 - 18528
Publicatiedatum: 28-10-2020
DOI: 10.1038/s41598-020-74485-z
Titel: Immune Regulation of Metabolic Homeostasis by Helminths and Their Molecules
Auteur(s): Hendrik J.P. van der Zande, Anna Zawistowska-Deniziak and Bruno Guigas
Tijdschrift: Trends in Parasitology
Start- en eindpagina: 795 - 808
Publicatiedatum: 01-10-2019
DOI: 10.1016/j.pt.2019.07.014
Titel: Schistosoma haematobium infection is
associated with lower serum cholesterol
levels and improved lipid profile in
overweight/obese individuals
Auteur(s): Jeannot F. Zinsou, Jacqueline J. Janse, Yabo Y. Honpkehedji, Jean
Claude Dejon-Agobe, Noemi Garcia-Tardon, Pytsje T. Hoekstra,
Marguerite Massinga-Loembe, Paul L. A. M. Corstjens, Govert J. van Dam, Martin Giera, Peter G. Kremsner, Maria Yazdanbakhsh, Ayola A. Adegnika, Bruno Guigas
Tijdschrift: PLoS Neglected Tropical Diseases
Start- en eindpagina: 1 - 16
Publicatiedatum: 02-07-2020
DOI: 10.1371/journal.pntd.0008464
Titel: The helminth glycoprotein omega-1 improves metabolic homeostasis in obese mice through
type-2 immunity-independent inhibition of food intake
Auteur(s): Hendrik J.P. van der Zande, Michael A. Gonzalez, Karin de Ruiter, Ruud H.P. Wilbers, Noemi Garcia-Tardón, Mariska van Huizen, Kim van Noort, Leonard R. Pelgrom, Joost M. Lambooij, Anna Zawistowska-Deniziak, Frank Otto, Arifa Ozir-Fazalalikhan, Danny van Willigen, Mick Welling, Jordan Poles, Fijs van Leeuwen, Cornelis H. Hokke, Arjen Schots, Maria Yazdanbakhsh, P’ng Loke, Bruno Guigas
Tijdschrift: BioRxiv
Start- en eindpagina: 1 - 32
Publicatiedatum: 03-07-2020
DOI: 10.1101/2020.07.03.186254
Titel: Soluble mannose receptor induces pro-inflammatory macrophage activation and metaflammation
Auteur(s): Maria Embgenbroich, Hendrik J.P. van der Zande, Leonie Hussaarts, Jonas Schulte-Schrepping, Leonard R. Pelgrom, Noemí García-Tardón, Laura Schlautmann, Isabel Stoetzel, Kristian Händler, Joost M. Lambooij, Anna Zawistowska-Deniziak, Lisa Hoving, Karin de Ruiter, Marjolein Wijngaarden, Hanno Pijl, Ko Willems van Dijk, Bart Everts, Vanessa van Harmelen, Maria Yazdanbakhsh, Joachim L. Schultze, Bruno Guigas, Sven Burgdorf
Tijdschrift: BioRxiv
Start- en eindpagina: 1 - 49
Publicatiedatum: 29-09-2020
DOI: 10.1101/2020.09.29.315598
Titel: Schistosome egg antigens, including the glycoprotein IPSE/alpha-1, trigger the development of regulatory B cells
Auteur(s): Haeberlein, Simone, Obieglo, Katja, Ozir-Fazalalikhan, Arifa, Chayé, Mathilde A. M., Veninga, Henrike, van der Vlugt, Luciën E. P. M., Voskamp, Astrid, Boon, Louis, den Haan, Joke M. M., Westerhof, Lotte B., Wilbers, Ruud H. P., Schots, Arjen, Schramm, Gabriele, Hokke, Cornelis H., Smits, Hermelijn H.
Tijdschrift: PLoS Pathogens
Start- en eindpagina: 1 - 28
Publicatiedatum: 28-07-2017
DOI: 10.1371/journal.ppat.1006539
Titel: Editorial - Parasites and metabolic diseases
Auteur(s): Guigas, B.
Tijdschrift: Parasite Immunology
Start- en eindpagina: 12432 - 12432
Publicatiedatum: 25-04-2017
DOI: doi: 10.1111/pim.12432
Titel: A worm of one's own: how helminths modulate host adipose tissue function and metabolism
Auteur(s): Guigas, Bruno, Molofsky, Ari B.
Tijdschrift: Trends in Parasitology
Start- en eindpagina: 435 - 441
Publicatiedatum: 01-09-2015
DOI: doi: 10.1016/j.pt.2015.04.008
Titel: Chronic helminth infection and helminth-derived egg antigens promote adipose tissue M2 macrophages and improve insulin sensitivity in obese mice
Auteur(s): Hussaarts, Leonie, García-Tardón, Noemí, van Beek, Lianne, Heemskerk, Mattijs M., Haeberlein, Simone, van der Zon, Gerard C., Ozir-Fazalalikhan, Arifa, Berbée, Jimmy F. P., Willems van Dijk, Ko, van Harmelen, Vanessa, Yazdanbakhsh, Maria, Guigas, Bruno
Tijdschrift: The FASEB Journal
Start- en eindpagina: 3027 - 3039
Publicatiedatum: 01-07-2015
DOI: doi: 10.1096/fj.14-266239
Titel: Production and glyco-engineering of immunomodulatory helminth glycoproteins in plants
Auteur(s): Wilbers, Ruud H. P., Westerhof, Lotte B., van Noort, Kim, Obieglo, Katja, Driessen, Nicole N., Everts, Bart, Gringhuis, Sonja I., Schramm, Gabriele, Goverse, Aska, Smant, Geert, Bakker, Jaap, Smits, Hermelijn H., Yazdanbakhsh, Maria, Schots, Arjen, Hokke, Cornelis H.
Tijdschrift: Scientific Reports
Start- en eindpagina: 45910 - 45910
Publicatiedatum: 10-04-2017
DOI: doi: 10.1038/srep45910
Titel: Helminths improve insulin sensitivity and enhance M2 macrophage numbers in WAT of obese mice
Auteur(s): Geach, T.
Tijdschrift: Nature Reviews Endocrinology
Start- en eindpagina: 316 - 316
Publicatiedatum: 01-06-2015
DOI: doi: 10.1038/nrendo.2015.68
Titel: De comeback van tabak als medicijn
Auteur(s): Peter de Jaeger
Tijdschrift: Het Parool
Start- en eindpagina: 53 - 53
Publicatiedatum: 08-07-2017
Titel: Wormen kunnen diabetes type 2 voorkomen
Auteur(s): Roefs, Maaike
Tijdschrift: DIABC
Start- en eindpagina: 23 - 23
Publicatiedatum: 01-03-2015
Titel: Snoep verstandig, eet een worm
Auteur(s): Braun, Bart
Tijdschrift: Mare
Start- en eindpagina: 7 - 7
Publicatiedatum: 11-06-2015
Titel: Stoffen uit wormeneitjes goed voor metabolisme
Auteur(s): LUMC communication department
Tijdschrift: LUMC Nieuwsbrief
Start- en eindpagina: 1 - 1
Publicatiedatum: 23-04-2015
Titel: Determination of Adenine Nucleotide Concentrations in Cells and Tissues by High-Performance Liquid Chromatography
Auteur(s): Noemí García-Tardón, Bruno Guigas
Start- en eindpagina: 229 - 237
Publicatiedatum: 27-02-2018
Titel: Assessing Mitochondrial Bioenergetics by Respirometry in Cells or Isolated Organelles
Auteur(s): Guillaume Vial, Bruno Guigas
Start- en eindpagina: 273 - 287
Publicatiedatum: 27-02-2018
Titel: Immune regulation of metabolic homeostasis
Auteur(s): Bruno Guigas
Publicatiedatum: 21-01-2019
Titel: Immune regulation of metabolic homeostasis by helminths and their molecules
Auteur(s): Bruno Guigas
Publicatiedatum: 06-12-2019
Titel: Immune regulation of metabolic homeostasis by helminths and their molecules
Auteur(s): Bruno Guigas
Publicatiedatum: 25-10-2019
Titel: Immune regulation of metabolic homeostasis by helminths and their molecules
Auteur(s): Bruno Guigas
Publicatiedatum: 30-10-2020
Titel: Interview in De Ochtendspits (BNR Nieuwsradio)
Auteur(s): Schots, Arjen
Publicatiedatum: 06-07-2017
Titel: Protective effects of parasite-derived molecules on metabolic disorders
Auteur(s): Guigas, Bruno
Publicatiedatum: 02-02-2016
Titel: Immune regulation of metabolic homeostasis:
from general concepts to therapeutic modulation by helminths
Auteur(s): Guigas, Bruno
Publicatiedatum: 17-07-2015
Titel: Immunomodulatory effects of parasites and metabolic syndrome
Auteur(s): Guigas, Bruno
Publicatiedatum: 28-10-2016
Titel: The Schistosoma mansoni glycoprotein omega-1 improves whole-body metabolic homeostasis independent of its Th2 polarizing capacity
Auteur(s): HENDRIK VAN DER ZANDE
Publicatiedatum: 07-09-2018
Titel: Phenotypically distinct alternatively-activated adipose tissue macrophages induced by helminth molecules differently impact metabolic homeostasis
Auteur(s): Hendrik J. P. van der Zande
Publicatiedatum: 29-05-2019
Titel: Phenotypically distinct alternatively-activated adipose tissue macrophages induced by helminth molecules differently impact metabolic homeostasis
Auteur(s): Bruno Guigas
Publicatiedatum: 15-04-2019
Titel: Immune regulation of metabolic homeostasis by parasite molecules
Auteur(s): Bruno Guigas
Publicatiedatum: 11-09-2020
Titel: Immune regulation of metabolic homeostasis by helminths and their molecules
Auteur(s): Bruno Guigas
Publicatiedatum: 20-09-2020
Titel: Immune regulation of metabolic homeostasis by helminths and their molecules
Auteur(s): Bruno Guigas
Publicatiedatum: 23-09-2020
Titel: Using plants to characterise Schistosoma mansoni fucosyltransferases
Auteur(s): van Noort, Kim
Publicatiedatum: 01-03-2018
Titel: Characterization of Schistosoma mansoni fucosyltransferases for glyco-engineering of
‘native’ helminth N-glycan structures in planta
Auteur(s): van Noort, Kim
Publicatiedatum: 18-09-2017
Titel: Characterization of Schistosoma mansoni fucosyltransferases for glyco-engineering of
‘native’ helminth N-glycan structures in planta
Auteur(s): van Noort, Kim
Publicatiedatum: 06-09-2017
Titel: Immune regulation of metabolic homeostasis by helminth molecules
Auteur(s): Guigas, Bruno
Publicatiedatum: 18-03-2018
Titel: Immune-dependent and -independent regulation of metabolic homeostasis by helminth molecules
Auteur(s): Guigas, Bruno
Publicatiedatum: 07-06-2017
Titel: Helminth antigens improve insulin sensitivity in obese mice by promoting a STAT6-dependent type 2 immune response in white adipose tissue
Auteur(s): van der Zande, Patrick
Publicatiedatum: 18-05-2017
Titel: The Schistosoma mansoni glycoprotein omega-1 improves whole-body metabolic homeostasis independent of its Th2 polarizing capacity
Auteur(s): van der Zande, Patrick
Publicatiedatum: 30-11-2017
Titel: Helminth antigens improve insulin sensitivity in obese mice by promoting a STAT6-dependent type 2 immune response in white adipose tissue
Auteur(s): van der Zande, Patrick
Publicatiedatum: 27-01-2017
Titel: Characterization of Schistosoma mansoni fucosyltransferases for glyco-engineering of ‘native’ helminth N-glycan structures in planta
Auteur(s): van Noort, Kim
Wilbers, Ruud H.P.
ter Horst, Kasper
Westerhof, Lotte B.
Hokke, Cornelis H.
Smant, G.
Bakker, J
Schots, Arjen
Publicatiedatum: 03-10-2016
Titel: Engineering of plants for the expression of helminth glycoproteins with their native N-glycan structures
Auteur(s): Wilbers, Ruud H.P.
Westerhof, Lotte B.
van Noort, Kim
Nguyen, D-L.
Bakker, J.
Hokke, Cornelis H.
Schots, Arjen
Publicatiedatum: 25-05-2016
Titel: Characterization of Schistosoma mansoni fucosyltransferases for glyco-engineering of ‘native’ helminth N-glycan structures in planta
Auteur(s): Van Noort, Kim
Wilbers, Ruud H.P.
Westerhof, Lotte B.
Smant, G
Bakker, J
Schots, Arjen
Publicatiedatum: 25-05-2016
Titel: Direct regulation of hepatic gluconeogenesis by helminth-derived molecules
Auteur(s): Guigas, Bruno
Publicatiedatum: 16-09-2016
Titel: Helminth antigens improve insulin sensitivity in obese mice by promoting a STAT6-dependent type 2 immune response in white adipose tissue
Auteur(s): van der Zande, Patrick
Publicatiedatum: 16-12-2016
Titel: Immune regulation of metabolic homeostasis by helminths
Auteur(s): Guigas, Bruno
Publicatiedatum: 15-11-2015
Titel: Chronic treatment with helminth-derived egg antigens improves whole-body metabolic homeostasis and insulin sensitivity in obese mice
Auteur(s): Garcia-Tardon, Noemi
Publicatiedatum: 27-05-2015
Titel: Immune regulation of metabolic homeostasis by helminths
Auteur(s): Guigas, Bruno
Publicatiedatum: 30-08-2015
Titel: "One triple shot americano and a coconut-chocolate-oats bar, please"; de effecten van parasitaire wormen op de stofwisseling
Auteur(s): van der Zande, Patrick
Publicatiedatum: 31-03-2017
Titel: Helminth infection and metabolic syndrome
Auteur(s): Guigas, Bruno
Publicatiedatum: 09-03-2016
Titel: Phenotypically distinct alternatively-activated adipose tissue macrophages induced by helminth molecules differently impact metabolic homeostasis
Auteur(s): H. J. P. van der Zande
Publicatiedatum: 22-02-2019
Titel: The helminth glycoprotein omega-1 improves whole-body metabolic homeostasis independent of its Th2 polarizing capacity
Auteur(s): Hendrik van der Zande, Michael Gonzalez, Mariska van Huizen, Karin de Ruiter, Ruud Wilbers, Lotte Westerhof, Arjen Schots, P’ng Loke, Maria Yazdanbakhsh, Bruno Guigas
Publicatiedatum: 24-06-2018
Titel: The Schistosoma mansoni glycoprotein omega-1 improves whole-body metabolic homeostasis independent of its Th2 polarizing capacity
Auteur(s): Hendrik van der Zande, Michael Gonzalez, Mariska van Huizen, Karin de Ruiter, Ruud Wilbers, Lotte Westerhof, Arjen Schots, P’ng Loke, Maria Yazdanbakhsh, Bruno Guigas
Publicatiedatum: 12-12-2017
Titel: Engineering of plants for the expression of helminth glycoproteins with their native N-glycan structures
Auteur(s): Wilbers, Ruud H.P.
Westerhof, Lotte B.
Everts, Bart
van Noort, Kim
van Raaij, Debbie R.
Nguyen, Dieu-Linh
Yazdanbakhsh, Maria
Hokke, Cornelis H.
Schots, Arjen
Publicatiedatum: 01-09-2015
Titel: Characterization of Schistosoma mansoni fucosyltransferases for glyco-engineering of ‘native’ helminth N-glycan structures in planta
Auteur(s): Van Noort, Kim
Wilbers, Ruud H.P.
Westerhof, Lotte B.
Smant, G.
Bakker, J.
Schots, Arjen
Publicatiedatum: 01-06-2016
Titel: Engineering of plants for the expression of helminth glycoproteins with their native N-glycan structures
Auteur(s): Wilbers, Ruud H.P.
Westerhof, Lotte B.
Everts, Bart
van Noort, Kim
van Raaij, Debbie R.
Nguyen, Dieu-Linh
Yazdanbakhsh, Maria
Hokke, Cornelis H.
Schots, Arjen
Publicatiedatum: 17-10-2016
Titel: Helminth antigens improve glucose tolerance in obese mice by promoting a STAT6-dependent type 2 immune response in white adipose tissue
Auteur(s): van der Zande Hendrik J.P.
Gonzalez Michael
Gundra, Uma M.
Lin Jian-Da
Hokke, Cornelis H.
Yazdanbakhsh, Maria
Loke, P’ng
Guigas, Bruno
Publicatiedatum: 01-05-2017
Titel: HelP-T2D / Helminth products for Type 2 Diabetes
Auteur(s): Bruno Guigas
Jantien Guldemond-Nieuwland
Publicatiedatum: 01-04-2015
URL:http://help-t2d.nl/